Flames broke out before 10:30 a.m. Friday at an apartment in the Wilson Houses on East 105th Street in Harlem.
Video from the scene shows firefighters working next to a charred window frame with a busted out window.
Officials said a 62-year-old man was found unresponsive and pronounced dead on the scene. A 93-year-old woman suffered a minor injury. The identities of the victims have not been released.
The fire appears to have originated on the building's third floor. It was placed under control around 11:00 a.m.
The cause of the fire is under investigation.
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