Earlier, hundreds of people could be seen marching through Midtown, Manhattan on 5th Avenue, stopping briefly in Times Square before continuing south on Broadway.
The group appeared to be mostly peaceful and the sentiment was that they want justice. Several protesters said the focus should be peace.
"Come in peace, say what you have to do, say what you have to say," one protester said. "Black lives matter. That's the message. Period. That's it. Look at this. Peaceful. That's all. Just hear us. Hear our cries."
At the same time, hundreds more protesters marched on Flatbush Avenue in Brooklyn, making their way toward Barclays Center. Protesters had been gathering outside the Barclays Center throughout the day where police remained on the perimeter.
At times, police and protesters shared moments of peace, kneeling together and even hugging.
Eventually, protesters marched across the Manhattan Bridge, stopping all lanes of traffic, as they chanted "Black Lives Matter." Other protesters marched across the Brooklyn Bridge, while another group crossed the Williamsburg Bridge.
Shutting down the Manhattan Bridge. pic.twitter.com/cRl4C3dXBc— Jason Rosenberg (@mynameisjro) June 1, 2020
In Lower Manhattan, the protesters converged and faced a mass of police officers, but the situation while tense remained non-violent.
Cops corned us on 2 sides and tried to block the street. Police in riot gear threatened us if we took another step so the ENTIRE group dropped to a knee. Kept it peaceful and now they opened the streets. We march on #NYCPROTEST #JusticeForGeorgeFloyd pic.twitter.com/Xlu8fAie1H— Chris Peary (@chris_peary24) June 1, 2020
By 9:30 p.m., tension gave way to some clashes with police, at least one vehicle fire and looting. One fire burned near the Strand Bookstore. Looters were spotted breaking into a Balenciaga store on Mercer Street.
On Saturday, largely peaceful protests around the city also gave way to scattered clashes between police and protesters later in the evening.
Demonstrators smashed shop windows, threw objects at officers, torched and battered police vehicles and blocked roads.
The mayor blamed much of the violence on a small group of well-organized "anarchists."
He described them as "people who came to do violence in a systematic and organized fashion." He denounced "an explicit agenda of violence" among some "anarchist movement" protesters and, overall, he said the NYPD demonstrated "tremendous restraint."
There was no loss of life and no major injuries on Saturday, he said.
Multiple police vehicles were set on fire or defaced with graffiti, while 345 people were arrested.
Mayor de Blasio's daughter, Chiara, was among the protesters arrested Saturday night, according to NYPD sources.
Chiara de Blasio was arrested about 10:30 p.m. Saturday for unlawful assembly.
Daytime marches blocked traffic but were mainly peaceful evolved at night into projectile throwing and the torching of police vehicles. 47 sustained damaged, officials said.
33 police officers were injured in demonstrations throughout parts of Brooklyn and Manhattan.
Police faced criticism after video circulated on social media that appeared to show a police SUV pushing a metal barrier into a crowd of demonstrators. Mayor de Blasio said in a late night news conference Saturday the police were put in an impossible situation.
Mayor Bill de Blasio called for an investigation.
"There were many things done right by the NYPD, there were also mistakes that must be investigated," he said.
De Blasio added many protestors were out of control putting officers in bad positions.
"You have to be in those officers' shoes," NYPD Police Commissioner Shea said of the footage.
The investigation will be led by the city's corporation counsel and Department of Investigation commissioner.
Earlier, Shea on Twitter applauded the efforts of police officers under extreme circumstances.
"What we saw in New York City last night and the night before was not about peaceful protest of any kind. It was not about civil disobedience. It was not about demonstrating against police brutality," he wrote. "What it was, quite frankly, was a mob bent solely on taking advantage of a moment in American history, to co-opt the cause of equality that we all must uphold, to intentionally inflict chaos, mayhem, and injury just for the sake of doing so."
To the Members of the NYPD:— Commissioner Shea (@NYPDShea) May 31, 2020
What you’ve endured these last couple of days and nights—like much of 2020, so far—was unprecedented. In no small way, I want you to know that I’m extremely proud of the way you’ve comported yourselves in the face of such persistent danger... pic.twitter.com/1ez0Ar17Ex
In Flatbush, police had to use pepper spray because some people in the crowd resorted to throwing bottles and other objects at officers, with more NYPD vehicles vandalized and set on fire.
On Friday night, video surfaced on social media showing a woman being violently shoved to the ground by an NYPD officer near the Barclays Center. In addition, two sisters from the Catskills were arrested for allegedly throwing a Molotov cocktail at an NYPD van occupied by four officers during Friday night's violent protests in Brooklyn. No one was burned.
Shea said his officers will work with demonstrators.
"We're going to make sure that everyone has the right to peacefully protest and assemble," Shea said said at a briefing with the mayor. "But we are not going to tolerate destruction of property, having our officers put into harm's way or any civilians put into harm's way."
Gov. Andrew Cuomo said the National Guard is on standby and that hundreds of additional troopers are being made available in Rochester and Buffalo.
"We expect additional protests tonight and we're preparing for such," Cuomo said at his daily briefing.
The governor also said state Attorney General Letitia James's investigation into actions by NYPD officers will include any protests held Sunday night.
Cuomo urged non-violence, saying "Burning down your own house never works and never makes sense...it dishonors Mr. Floyd's death. Mr. Floyd was not violent. Mr. Floyd was compliant."
Similar protests flared around the nation in response to the Minnesota death of George Floyd. Floyd, who was black, died Monday after a white Minneapolis police officer pressed his knee on his neck until he stopped breathing.
NYPD vehicle drives into group of Brooklyn protesters
Video shows NYPD officer shoving woman to ground during Floyd protests
PHOTOS: George Floyd protests erupt into violence in NYC
Minneapolis Park Police release bodycam footage near George Floyd's in-custody death
3 people, including Catskills woman, face federal charges in Molotov police attacks: source
Brooklyn protests: Calls for review of violent protests, police response; hundreds arrested
1 federal officer killed, 1 critically hurt near California protest in 'act of domestic terrorism'
Derek Chauvin, police officer accused in George Floyd's death, charged with murder
Mayor de Blasio urges protesters to remain peaceful, socially distant
* More New York City news
* Send us a news tip
* Download the abc7NY app for breaking news alerts