It happened just after 2 p.m. Sunday on East 25th Street near the FDR Drive. The FDNY says 11 people were hurt, one of them seriously.
Flames started on the 14th floor inside the 29-story building on East 31st Street between Third and Lexington Avenues.
Police have arrested the man wanted after actor Steve Buscemi was punched in the face during a random attack in Manhattan.
Police identified the man as 50-year-old Clifton Williams.
Buscemi was walking on Third Avenue near 27th Street this past Wednesday when police say someone slugged him.
The suspects, believed to be 18 and 19 years old, were captured in Pennsylvania.